* Fakultas Farmasi, Universitas Padjadjaran, Bandung, Indonesia
**Pharmacore, Jakarta, Indonesia.
ABSTRACT
A study on formulation of antikeloidal ointments preparations within hydrocarbon ointment base and absorption ointment base contain of microwave-assisted extract from Pegagan herbs (Centella asiatica (L.) Urban) in hidroglycolic (80% and 60 %) mixture has been conducted. The yield of phytochemical analysis determined by thin layer chromatography showed that this method of extraction successfully extracts the main constituent of pegagan herbs known as triterpenoid components especially asiaticoside, asiatic acid and madecasic acid. The yield of examination of ointments preparations that has been made showed that both of these ointments are not irritable to use, where as in eight weeks of storage time, hydrocarbon based ointment has a constant homogeneity, odour, colour, viscosity and showed the decreasing pH. Likewise, the absorption based ointment has a constant homogeneity, odour and colour also showed the decreasing in pH and viscosity value, and statistically performed preferable ointment base.
Key words: antikeloidal ointments, microwave-assisted extraction, TLC, stability of ointments.
B I O D I V E R S I T A S ISSN: 1412-033X Volume 7, Nomor 1 Januari 2006
Halaman: 25-29
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